Cardiovascular CT Will Play a Critical Role in Addressing Top Research Priorities Outlined by NHLBI
As part of the National Heart, Lung, and Blood Institute’s (NHLBI) Strategic Vision, the institute recently unveiled its 8 key objectives and 132 top research priorities for guiding future directions in heart, lung, blood, and sleep research over the next decade. These research priorities will serve as a guide for resource allocation and will be regularly updated through ongoing engagement and iteration within the scientific community. Key themes include personalized precision medicine, early detection and disease prevention, elimination of health inequities, and leveraging the power of big data systems to diagnose, treat, and prevent disease.
Considering the robust data demonstrating its efficacy and precision, cardiovascular CT is an ideal tool for tackling many of NHLBI’s top research priorities, including compelling questions related to the pathophysiology of atherosclerotic heart disease, and addressing critical challenges in population health.
Examples of NHLBI priorities where cardiovascular CT may play an important role include:
- Exploring the pathobiology of aberrant calcification of coronary arteries, heart valves, and peripheral arteries, and understanding why calcification is associated with a poor prognosis
- Developing novel experimental strategies and tools for evaluating the effect of sex differences on cardiovascular health, resilience, and disease
- Developing clinical evaluation tools which can differentiate patients with atherosclerotic heart disease who will progress to myocardial infarction or with sudden cardiac death from those with stable disease
- Understanding how the pathobiology underlying nonobstructive ischemic heart disease and the associated risks for acute coronary syndrome and early mortality differs between subpopulations, and identifying targets for treatment and prevention
- Developing innovative approaches to private sector collaborations and partnerships in early diagnostic product development to bridge the gap between academic discoveries and product commercialization
The NHLBI Strategic Visioning plan and complete list of top research priorities can be reviewed here: https://www.nhlbi.nih.gov/about/documents/strategic-vision